0001047469-12-003243 Sample Contracts

ALLOS THERAPEUTICS, INC. SECOND AMENDMENT TO SECOND AMENDED AND RESTATED EMPLOYMENT AGREEMENT MARC H. GRABOYES
Employment Agreement • March 26th, 2012 • Allos Therapeutics Inc • Pharmaceutical preparations • Colorado

This SECOND AMENDMENT TO SECOND AMENDED AND RESTATED EMPLOYMENT AGREEMENT (this "Second Amendment") is entered into effective as of September 7, 2011, by and between ALLOS THERAPEUTICS, INC. (the "Company") and MARC H. GRABOYES ("Executive") (collectively, the "Parties").

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SIXTH AMENDMENT TO OFFICE LEASE AGREEMENT
Office Lease Agreement • March 26th, 2012 • Allos Therapeutics Inc • Pharmaceutical preparations

THIS SIXTH AMENDMENT TO OFFICE LEASE AGREEMENT (this "Amendment"), dated as of December 7, 2011, (the "Effective Date") is entered into by and between CIRCLE POINT PROPERTIES, LLC, a Delaware limited liability company (the "Landlord") and ALLOS THERAPEUTICS, INC., a Delaware corporation (the "Tenant").

THIRD AMENDMENT TO LEASE
Allos Therapeutics Inc • March 26th, 2012 • Pharmaceutical preparations

THIS THIRD AMENDMENT TO LEASE ("Amendment") is made and entered into as of the 28th day of November 2003, by and between CATELLUS DEVELOPMENT CORPORATION, a Delaware corporation ("Landlord"), and ALLOS THERAPEUTICS, INC., a Delaware corporation ("Tenant").

AMENDED AND RESTATED SECOND AMENDMENT TO LEASE
Allos Therapeutics Inc • March 26th, 2012 • Pharmaceutical preparations

THIS AMENDED AND RESTATED SECOND AMENDMENT TO LEASE ("Amendment") is made and entered into as of the 9th day of December, 2002, by and between CATELLUS DEVELOPMENT CORPORATION, a Delaware corporation ("Landlord"), and ALLOS THERAPEUTICS, INC., a Delaware corporation ("Tenant").

LICENSE, DEVELOPMENT AND COMMERCIALIZATION AGREEMENT by and between ALLOS THERAPEUTICS, INC., a Delaware corporation and MUNDIPHARMA INTERNATIONAL CORPORATION LIMITED a Bermuda corporation
License, Development and Commercialization Agreement • March 26th, 2012 • Allos Therapeutics Inc • Pharmaceutical preparations • New York

[ * ] = Certain confidential information contained in this document, marked by brackets, is filed with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

ALLOS THERAPEUTICS, INC. SECOND AMENDMENT TO EMPLOYMENT AGREEMENT CHARLES MORRIS
Employment Agreement • March 26th, 2012 • Allos Therapeutics Inc • Pharmaceutical preparations • Colorado

This SECOND AMENDMENT TO EMPLOYMENT AGREEMENT (this "Second Amendment") is entered into effective as of September 7, 2011, by and between ALLOS THERAPEUTICS, INC. (the "Company") and CHARLES MORRIS ("Executive") (collectively, the "Parties").

ALLOS THERAPEUTICS, INC. SECOND AMENDMENT TO EMPLOYMENT AGREEMENT MICHAEL E. SCHICK
Employment Agreement • March 26th, 2012 • Allos Therapeutics Inc • Pharmaceutical preparations • Colorado

This SECOND AMENDMENT TO EMPLOYMENT AGREEMENT (this "Second Amendment") is entered into effective as of September 7, 2011, by and between ALLOS THERAPEUTICS, INC. (the "Company") and MICHAEL E. SCHICK ("Executive") (collectively, the "Parties").

ALLOS THERAPEUTICS, INC. SECOND AMENDMENT TO EMPLOYMENT AGREEMENT BRUCE K. BENNETT, JR.
Employment Agreement • March 26th, 2012 • Allos Therapeutics Inc • Pharmaceutical preparations • Colorado

This SECOND AMENDMENT TO EMPLOYMENT AGREEMENT (this "Second Amendment") is entered into effective as of September 6, 2011, by and between ALLOS THERAPEUTICS, INC. (the "Company") and BRUCE K. BENNETT, JR. ("Executive") (collectively, the "Parties").

ALLOS THERAPEUTICS, INC. SECOND AMENDMENT TO EMPLOYMENT AGREEMENT DAVID CLARK
Employment Agreement • March 26th, 2012 • Allos Therapeutics Inc • Pharmaceutical preparations • Colorado

This SECOND AMENDMENT TO EMPLOYMENT AGREEMENT (this "Second Amendment") is entered into effective as of September 7, 2011, by and between ALLOS THERAPEUTICS, INC. (the "Company") and DAVID CLARK ("Executive") (collectively, the "Parties").

FIFTH AMENDMENT TO OFFICE LEASE AGREEMENT
Office Lease Agreement • March 26th, 2012 • Allos Therapeutics Inc • Pharmaceutical preparations

THIS FIFTH AMENDMENT TO OFFICE LEASE AGREEMENT (this "Amendment"), dated as of June 16, 2008, (the "Effective Date") is entered into by and between CIRCLE POINT PROPERTIES, LLC, a Delaware limited liability company (the "Landlord") and ALLOS THERAPEUTICS, INC., a Delaware corporation (the "Tenant").

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